Ian Collins Selected Research

3-methoxybenzamide

1/2013

An improved small-molecule inhibitor of FtsZ with superior in vitro potency, drug-like properties, and in vivo efficacy.

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Ian Collins Research Topics

Disease

32	Neoplasms (Cancer) 06/2022 - 08/2005
3	AIDS-Related Complex (ARC) 12/2019 - 01/2017
3	Arthrogryposis renal dysfunction cholestasis syndrome 12/2019 - 01/2017
3	Breast Neoplasms (Breast Cancer) 01/2019 - 02/2011
2	Osteosarcoma (Osteogenic Sarcoma) 10/2022 - 06/2005
2	Neoplasm Metastasis (Metastasis) 01/2022 - 06/2015
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2020
2	Obesity 01/2016 - 07/2012
2	Hypoxia (Hypoxemia) 01/2016 - 06/2005
2	Colonic Neoplasms (Colon Cancer) 01/2011 - 08/2009
1	Hepatocellular Carcinoma (Hepatoma) 10/2022
1	Lymphoma (Lymphomas) 10/2022
1	Hypotension (Low Blood Pressure) 01/2020
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2020
1	Febrile Neutropenia 01/2019
1	Fatigue 01/2019
1	Neutropenia 01/2019
1	Pneumothorax 01/2019
1	B-Cell Lymphoma (Lymphoma, B Cell) 01/2016
1	Inflammation (Inflammations) 01/2016
1	Melanoma (Melanoma, Malignant) 06/2015
1	Aneuploidy (Aneuploid) 03/2013
1	Multiple Myeloma 03/2013
1	Staphylococcal Infections 01/2013
1	Neuroblastoma 10/2012
1	Carcinoma (Carcinomatosis) 12/2011
1	Glioblastoma (Glioblastoma Multiforme) 02/2011
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 01/2011
1	Lung Neoplasms (Lung Cancer) 01/2011
1	Infections 09/2008

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 10/2022 - 06/2005
9	Phosphotransferases (Kinase)IBA 06/2015 - 08/2005
4	Biomarkers (Surrogate Marker)IBA 01/2020 - 03/2010
4	Gemcitabine FDA Link 01/2016 - 01/2010
3	3- ((1- (dimethylamino)propan- 2- yl)oxy)- 5- ((4- methoxy- 5- (1- methyl- 1H- pyrazol- 4- yl)pyridin- 2- yl)amino)pyrazine- 2- carbonitrileIBA 10/2022 - 10/2012
3	Molecular Chaperones (Chaperone, Molecular)IBA 01/2022 - 01/2008
3	Peptides (Polypeptides)IBA 12/2019 - 01/2017
3	TankyrasesIBA 12/2019 - 01/2017
3	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2019 - 01/2010
3	LigandsIBA 07/2012 - 03/2007
3	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2009 - 10/2006
2	Heat-Shock Proteins (Heat-Shock Protein)IBA 01/2022 - 10/2016
2	AT13148IBA 01/2020 - 06/2015
2	EnzymesIBA 12/2019 - 01/2017
2	Protein Kinase InhibitorsIBA 09/2013 - 08/2009
2	Irinotecan (Camptosar)FDA LinkGeneric 10/2012 - 12/2011
2	Trastuzumab (Herceptin)FDA Link 01/2012 - 12/2006
2	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2011 - 06/2005
2	Antineoplastic Agents (Antineoplastics)IBA 03/2010 - 01/2010
1	Proto-Oncogene Proteins B-rafIBA 06/2022
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2022
1	AphidicolinIBA 01/2020
1	SRA737IBA 01/2020
1	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 01/2020
1	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2020
1	CateninsIBA 12/2019
1	Albumin-Bound Paclitaxel FDA Link 01/2019
1	Transaminases (Aminotransferases)IBA 01/2019
1	Arginine (L-Arginine)FDA Link 01/2019
1	Cyclophosphamide (Cytoxan)FDA LinkGeneric 01/2019
1	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2019
1	Epirubicin (Ellence)FDA LinkGeneric 01/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2017
1	UbiquitinIBA 01/2017
1	CCT245737IBA 01/2016
1	AICA ribonucleotide (ZMP)IBA 01/2016
1	PalmitatesIBA 01/2016
1	Adenosine Monophosphate (AMP)IBA 01/2016
1	CytokinesIBA 01/2016
1	KinesinsIBA 01/2016
1	Fatty Acids (Saturated Fatty Acids)IBA 01/2016
1	rho-Associated KinasesIBA 06/2015
1	SAR 020106IBA 03/2013
1	EndoribonucleasesIBA 03/2013
1	Ribonucleases (Ribonuclease)IBA 03/2013
1	Messenger RNA (mRNA)IBA 03/2013
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2013
1	3-methoxybenzamideIBA 01/2013
1	Succinic Acid (Succinate)IBA 01/2013
1	ProdrugsIBA 01/2013
1	isoquinolineIBA 12/2011
1	Adenosine Triphosphate (ATP)IBA 03/2011
1	4- (4- chlorobenzyl)- 1- (7H- pyrrolo(2,3- d)pyrimidin- 4- yl)piperidin- 4- amineIBA 02/2011
1	4- fluoro- 2- (4- (4- (2- hydroxypropan- 2- yl)pyrrolidin- 3- ylamino)- 6,7- dimethoxyquinazolin- 2- yl)phenolIBA 01/2011
1	Insulin (Novolin)FDA Link 01/2011
1	Coloring Agents (Dyes)IBA 01/2011
1	Etoposide (VP 16)FDA LinkGeneric 01/2010
1	Drug CombinationsIBA 01/2010
1	purineIBA 08/2009
1	PC190723IBA 09/2008
1	5- (2,4- dihydroxy- 5- isopropylphenyl)- 4- (4- morpholin- 4- ylmethylphenyl)isoxazole- 3- carboxylic acid ethylamideIBA 01/2008
1	Bevacizumab (Avastin)FDA Link 12/2006
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 12/2006

Therapy/Procedure

10	Therapeutics 01/2020 - 12/2006
3	Drug Therapy (Chemotherapy) 06/2013 - 01/2010
1	Neoadjuvant Therapy 01/2019
1	Intradermal Injections 06/2015
1	Radiotherapy 06/2013
1	Oral Administration 10/2012
1	Precision Medicine 12/2006